PrimePCR™ ddPCR™ Expression EvaGreen® Assay: Akt1, Mouse

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qMmuCID0023089; Intron-spanning

List Price:    $142.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dMmuEG5084797
Chromosome Location:   12:112655173-112656549question
Amplicon Length:   75

Gene Information

This gene encodes the founding member of the Akt serine-threonine protein kinase gene family that also includes Akt2 and Akt3. This kinase is a major downstream effector of the phosphatidylinositol 3-kinase (PI3K) pathway that mediates the effects of various growth factors such as platelet-derived growth factor (PDGF) epidermal growth factor (EGF) insulin and insulin-like growth factor I (IGF-I). It is activated through recruitment to cellular membranes by PI3K lipid products and by phosphorylation by 3-phosphoinositide dependent kinase-1. It then further phosphorylates different downstream proteins in response to various extracellular signals and thus plays a pivotal role in mediating a variety of cellular processes such as glucose metabolism glycogen biosynthesis protein synthesis and turn over inflammatory response cell survival (anti-apoptosis) and development. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Sep 2009]

Gene Symbol:   Akt1
Gene Name:   Thymoma viral proto-oncogene 1
Aliases:   Akt, PKB, PKB/Akt, PKBalpha, Rac
RefSeq:   NC_000078.6 NT_039551.8
Ensembl:   ENSMUSG00000001729
Entrez:   11651
UniGene:   Mm.6645
Chromosome Mapping:   12 F1|12 57.0 cM

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