PrimePCR™ ddPCR™ Expression EvaGreen® Assay: Abcd2, Mouse

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qMmuCID0021834; Intron-spanning

List Price:    $142.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dMmuEG5083687
Chromosome Location:   15:91149134-91151708question
Amplicon Length:   96

Gene Information

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1 MDR/TAP MRP ALD OABP GCN20 White). This protein is a member of the ALD subfamily which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown; however this protein is speculated to function as a dimerization partner of Abcd1 and/or other peroxisomal ABC transporters. Mutations in the human gene have been observed in patients with adrenoleukodystrophy a severe demyelinating disease. This gene has been identified as a candidate for a modifier gene accounting for the extreme variation among adrenoleukodystrophy phenotypes. This gene is also a candidate for a complement group of Zellweger syndrome a genetically heterogeneous disorder of peroxisomal biogenesis. [provided by RefSeq Jul 2008]

Gene Symbol:   Abcd2
Gene Name:   ATP-binding cassette, sub-family D (ALD), member 2
Aliases:   ABC39, ALDL1, ALDR, ALDRP
RefSeq:   NC_000081.6 NT_039621.8
Ensembl:   ENSMUSG00000055782
Entrez:   26874
UniGene:   Mm.295456
Chromosome Mapping:   15 E-F|15

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