PrimePCR™ ddPCR™ Expression EvaGreen® Assay: Psen2, Mouse

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qMmuCID0006082; Intron-spanning

List Price:    $138.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dMmuEG5073313
Chromosome Location:   1:180235168-180238912question
Amplicon Length:   120

Gene Information

This gene encodes a member of the presenilin family. Presenilins are catalytic components of the multi-subunit gamma-secretase complex which mediates critical cellular processes through cleavage of type I transmembrane proteins including Notch receptors and the amyloid precursor protein. The encoded protein contains eight transmembrane domains and is localized to the endoplasmic reticulum where it may play a role in calcium homeostasis. Following assembly of the gamma-secretase complex the encoded protein is cleaved into N- and C-terminal fragments and the activated complex is released from the endoplasmic reticulum. Inactivation of this gene results in impaired synaptic function in a mouse model for Alzheimer's disease. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq Apr 2011]

Gene Symbol:   Psen2
Gene Name:   Presenilin 2
Aliases:   ALG-3, Ad4h, Alg3, PS-2, PS2, Psnl2, STM2
RefSeq:   NC_000067.6 NT_039185.8
Ensembl:   ENSMUSG00000010609
Entrez:   19165
UniGene:   Mm.330850
Chromosome Mapping:   1 H4|1 101.0 cM

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