PrimePCR™ ddPCR™ Expression EvaGreen® Assay: Trp73, Mouse

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qMmuCID0006017; Intron-spanning

List Price:    $138.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dMmuEG5073276
Chromosome Location:   4:154064673-154067041question
Amplicon Length:   77

Gene Information

This gene encodes tumor protein p73 which is a member of the p53 family of transcription factors involved in cellular responses to stress and development. The family members include p53 p63 and p73 and have high sequence similarity to one another which allows p63 and p73 to transactivate p53-responsive genes causing cell cycle arrest and apoptosis. The family members can interact with each other in many ways involving direct or indirect protein interactions resulting in regulation of the same target gene promoters or regulation of each other's promoters. The p73 protein is expressed at very low levels in normal tissues and is differentially expressed in a number of tumors. The p73 gene expresses at least 35 mRNA variants due to the use of alternate promoters alternate translation initiation sites and multiple splice variations. Theoretically this can account for 29 different p73 isoforms; however the biological validity and the full-length nature of most variants have not been determined. [provided by RefSeq Jul 2008]

Gene Symbol:   Trp73
Gene Name:   Transformation related protein 73
Aliases:   Tp73, p73
RefSeq:   NC_000070.6 NT_187033.1
Ensembl:   ENSMUSG00000029026
Entrez:   22062
UniGene:   Mm.78015
Chromosome Mapping:   4 E2|4 82.0 cM

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