PrimePCR™ ddPCR™ Expression EvaGreen® Assay: Rp1, Mouse

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qMmuCED0039687; exonic

List Price:    $138.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dMmuEG5063388
Chromosome Location:   1:4352706-4360201question
Amplicon Length:   103

Gene Information

This gene encodes a member of the doublecortin family. The protein encoded by this gene contains two doublecortin domains which bind microtubules and regulate microtubule polymerization. The encoded protein is a photoreceptor microtubule-associated protein and is required for correct stacking of outer segment disc. This protein and the RP1L1 protein another retinal-specific protein play essential and synergistic roles in affecting photosensitivity and outer segment morphogenesis of rod photoreceptors. Because of its response to in vivo retinal oxygen levels this protein was initially named ORP1 (oxygen-regulated protein-1). This protein was subsequently designated RP1 (retinitis pigmentosa 1) when it was found that mutations in this gene cause autosomal dominant retinitis pigmentosa. Mutations in this gene also cause autosomal recessive retinitis pigmentosa. Two transcript variants encoding distinct isoforms are resulted from alternative promoters and alternative splicing. [provided by RefSeq Sep 2010]

Gene Symbol:   Rp1
Gene Name:   Retinitis pigmentosa 1 (human)
Aliases:   Dcdc3, Orp1, Rp1h, mG145
RefSeq:   NC_000067.6 NT_039169.8
Ensembl:   ENSMUSG00000025900
Entrez:   19888
UniGene:   Mm.294263
Chromosome Mapping:   1 A1|1 6.5 cM

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