PrimePCR™ ddPCR™ Expression Probe Assay: Cldn11, Mouse


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qMmuCIP0036261; Intron-spanning

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dMmuCPE5123086
Chromosome Location:   3:31154033-31163122question
Amplicon Length:   63

Gene Information

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is a major component of CNS (central nervous system) myelin and plays an important role in regulating proliferation and migration of oligodendrocytes. The basal cell tight junctions in stria vascularis are primarily composed of this protein and the gene-null mice suffer severe deafness. This protein is also an obligatory protein for tight junction formation and barrier integrity in the testis and the gene deficiency results in loss of the Sertoli cell epithelial phenotype in the testis. [provided by RefSeq Aug 2010]

Gene Symbol:   Cldn11
Gene Name:   Claudin 11
Aliases:   Claudin-11, Claudin11, Osp, Otm
RefSeq:   NC_000069.6 NT_162143.4
Ensembl:   ENSMUSG00000037625
Entrez:   18417
UniGene:   Mm.4425
Chromosome Mapping:   3 A3|3 12.6 cM

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