PrimePCR™ ddPCR™ Expression Probe Assay: Abcb11, Mouse

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qMmuCIP0035533; Intron-spanning

 
Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dMmuCPE5121752
Chromosome Location:   2:69259663-69261410question
Amplicon Length:   80

Gene Information

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1 MDR/TAP MRP ALD OABP GCN20 White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt transporter in humans and mice. Mutations in the human gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy. [provided by RefSeq Jul 2008]

Gene Symbol:   Abcb11
Gene Name:   ATP-binding cassette, sub-family B (MDR/TAP), member 11
Aliases:   ABC16, Bsep, Lith1, PFIC2, PGY4, SPGP
RefSeq:   NC_000068.7 NT_039207.8
Ensembl:   ENSMUSG00000027048
Entrez:   27413
UniGene:   Mm.439855
Chromosome Mapping:   2 C2|2 38.4 cM

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