PrimePCR™ ddPCR™ Expression Probe Assay: Obscn, Mouse


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qMmuCIP0034340; Intron-spanning

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dMmuCPE5119997
Chromosome Location:   11:59022307-59027470question
Amplicon Length:   120

Gene Information

The obscurin gene spans more than 150 kb contains over 80 exons and encodes a protein of approximately 800 kDa. The encoded protein contains 68 Ig domains 2 fibronectin domains 1 calcium/calmodulin-binding domain 1 RhoGEF domain with an associated PH domain and 2 serine-threonine kinase domains. This protein is one of three giant sacromeric signaling proteins that includes titin and nebulin. It may have a role in the organization of myofibrils during assembly and also may mediate interactions between the sarcoplasmic reticulum and myofibrils. Alternatively spliced transcript variants encoding different isoforms have been described although the full-length nature is not known for all splicing variants. [provided by RefSeq Jan 2010]

Gene Symbol:   Obscn
Gene Name:   Obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Aliases:   BC046431, Gm878, OTTMUSG00000005786, UNC89
RefSeq:   NC_000077.6 NT_096135.6
Ensembl:   ENSMUSG00000061462
Entrez:   380698
UniGene:   Mm.339542
Chromosome Mapping:   11 B1.3|11

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