PrimePCR™ ddPCR™ Expression Probe Assay: Dclk2, Mouse

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qMmuCIP0033808; Intron-spanning

 
Fluorophore:   FAM
List Price:    $207.00
Your Price:   Log In
 

Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dMmuCPE5118988
Chromosome Location:   3:86906178-86919822question
Amplicon Length:   82

Gene Information

This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains which bind microtubules and regulate microtubule polymerization a C-terminal serine/threonine protein kinase domain which shows substantial homology to Ca2+/calmoduline-dependent protein kinase and a serine/proline-rich domain in between the doublecortin and the protein kinase domains which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. This gene and the DCX gene another family member share function in the establishment of hippocampal organization and their absence results in a severe epileptic phenotype and lethality as described in human patients with lissencephaly. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq Sep 2010]

Gene Symbol:   Dclk2
Gene Name:   Doublecortin-like kinase 2
Aliases:   6330415M09Rik, AU044875, CL2, CLICK2, Click-II, Dcamkl2
RefSeq:   NC_000069.6 NT_039240.8
Ensembl:   ENSMUSG00000028078
Entrez:   70762
UniGene:   Mm.44490
Chromosome Mapping:   3 F1|3

Number Description Download