PrimePCR™ ddPCR™ Expression Probe Assay: Crbn, Mouse


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qMmuCIP0030420; Intron-spanning

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dMmuCPE5113247
Chromosome Location:   6:106790873-106794211question
Amplicon Length:   113

Gene Information

This gene encodes a protein with a Lon protease domain a "regulators of G protein-signaling" (RGS)-like domain and a leucine zipper. It has been proposed to regulate the assembly and surface expression of large-conductance calcium-activated potassium channels in brain and to bind thalidomide. In humans mutation in this gene causes autosomal recessive nonsyndromic mental retardation. In mouse deficiency of this gene serves as a model to study the molecular mechanisms governing learning and memory as they relate to intellectual disability. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq Jan 2013]

Gene Symbol:   Crbn
Gene Name:   Cereblon
Aliases:   2610203G15Rik, 2900045O07Rik, AF229032, AW108261, piL
RefSeq:   NC_000072.6 NT_039353.8
Ensembl:   ENSMUSG00000005362
Entrez:   58799
UniGene:   Mm.290085
Chromosome Mapping:   6 E2|6

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