PrimePCR™ ddPCR™ Expression Probe Assay: Birc5, Mouse


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qMmuCIP0029624; Intron-spanning

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dMmuCPE5111791
Chromosome Location:   11:117849786-117852749question
Amplicon Length:   135

Gene Information

This gene is a member of the inhibitor of apoptosis (IAP) gene family which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. In humans gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts have been identified in human that regulate this gene's expression. At least three transcript variants encoding distinct isoforms have been found for this gene although at least one of these transcript variants is a nonsense-mediated decay (NMD) candidate. [provided by RefSeq Jul 2008]

Gene Symbol:   Birc5
Gene Name:   Baculoviral IAP repeat-containing 5
Aliases:   AAC-11, Api4, TIAP, survivin40
RefSeq:   NC_000077.6 NT_096135.6
Ensembl:   ENSMUSG00000017716
Entrez:   11799
UniGene:   Mm.8552
Chromosome Mapping:   11|11 E2

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