PrimePCR™ ddPCR™ Expression Probe Assay: Abcb1b, Mouse


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qMmuCEP0055974; exonic

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dMmuCPE5098908
Chromosome Location:   5:8865881-8865978question
Amplicon Length:   68

Gene Information

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1 MDR/TAP MRP ALD OABP GCN20 White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene encodes a membrane glycoprotein which confers a multidrug-resistance phenotype. The protein encoded by the human gene is an ATP-dependent drug efflux pump for xenobiotic compounds which is responsible for decreased drug accumulation in multidrug-resistant cells and mediates the development of resistance to anticancer drugs. [provided by RefSeq Jul 2008]

Gene Symbol:   Abcb1b
Gene Name:   ATP-binding cassette, sub-family B (MDR/TAP), member 1B
Aliases:   Abcb1, Mdr1, Mdr1b, Pgy-1, Pgy1, mdr
RefSeq:   NC_000071.6 NT_039299.7
Ensembl:   ENSMUSG00000028970
Entrez:   18669
UniGene:   Mm.146649
Chromosome Mapping:   5 1.0 cM

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