PrimePCR™ ddPCR™ Expression Probe Assay: Rp1, Mouse


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qMmuCEP0041908; exonic

Fluorophore:   HEX
List Price:    $207.00
Your Price:   Log In

Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dMmuCPE5090407
Chromosome Location:   1:4352706-4360201question
Amplicon Length:   103

Gene Information

This gene encodes a member of the doublecortin family. The protein encoded by this gene contains two doublecortin domains which bind microtubules and regulate microtubule polymerization. The encoded protein is a photoreceptor microtubule-associated protein and is required for correct stacking of outer segment disc. This protein and the RP1L1 protein another retinal-specific protein play essential and synergistic roles in affecting photosensitivity and outer segment morphogenesis of rod photoreceptors. Because of its response to in vivo retinal oxygen levels this protein was initially named ORP1 (oxygen-regulated protein-1). This protein was subsequently designated RP1 (retinitis pigmentosa 1) when it was found that mutations in this gene cause autosomal dominant retinitis pigmentosa. Mutations in this gene also cause autosomal recessive retinitis pigmentosa. Two transcript variants encoding distinct isoforms are resulted from alternative promoters and alternative splicing. [provided by RefSeq Sep 2010]

Gene Symbol:   Rp1
Gene Name:   Retinitis pigmentosa 1 (human)
Aliases:   Dcdc3, Orp1, Rp1h, mG145
RefSeq:   NC_000067.6 NT_039169.8
Ensembl:   ENSMUSG00000025900
Entrez:   19888
UniGene:   Mm.294263
Chromosome Mapping:   1 A1|1 6.5 cM

Number Description Download