PrimePCR™ ddPCR™ Expression Probe Assay: Pcdh8, Mouse


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qMmuCEP0028037; Exonic

Fluorophore:   FAM
List Price:    $207.00
Your Price:   Log In

Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dMmuCPE5088562
Chromosome Location:   14:79768153-79768281question
Amplicon Length:   99

Gene Information

This gene belongs to the protocadherin gene family a subfamily of the cadherin superfamily. The gene encodes a type I transmembrane protein composed of an extracellular domain including 6 cadherin ectodomains a single-pass transmembrane domain and a cytoplasmic tail. Unlike classical cadherins which are generally encoded by 15-17 exons this gene includes only 3 exons with the first large exon encoding the extracellular and transmembrane region. Although this gene product is capable of homophilic interaction it appears to affect cell-cell adhesion indirectly by initiating signaling events that regulate classical cadherin-mediated adhesion. Based on studies on this protein and its orthologs this protocadherin mainly functions in developing embryos and the central nervous system but can also function as a tumor suppressor. Alternative splicing yielding isoforms with unique cytoplasmic tails has been reported. [provided by RefSeq Sep 2009]

Gene Symbol:   Pcdh8
Gene Name:   Protocadherin 8
Aliases:   1700080P15Rik, Papc
RefSeq:   NC_000080.6 NT_039606.8
Ensembl:   ENSMUSG00000036422
Entrez:   18530
UniGene:   Mm.390715
Chromosome Mapping:   14 D3|14 43.0 cM

Number Description Download