PrimePCR™ ddPCR™ Expression EvaGreen® Assay: MMP13, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0008487; Intron-spanning

List Price:    $138.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5015679
Chromosome Location:   11:102820839-102822790question
Amplicon Length:   138

Gene Information

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes such as embryonic development reproduction and tissue remodeling as well as in disease processes such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq Jul 2008]

Gene Symbol:   MMP13
Gene Name:   matrix metallopeptidase 13 (collagenase 3)
Aliases:   CLG3, MANDP1
RefSeq:   NC_000011.9 NG_021404.1 NT_033899.8
Ensembl:   ENSG00000137745
Entrez:   4322
UniGene:   Hs.2936
Chromosome Mapping:   11q22.3

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