PrimePCR™ ddPCR™ Expression EvaGreen® Assay: SLC12A1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCID0006522; Intron-spanning

List Price:    $138.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5014524
Chromosome Location:   15:48522590-48524985question
Amplicon Length:   143

Gene Information

This gene encodes a kidney-specific sodium-potassium-chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle's loop and the macula densa. It plays a key role in concentrating urine and accounts for most of the NaCl resorption. It is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in this gene. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity in humans has not been experimentally proven.[provided by RefSeq May 2010]

Gene Symbol:   SLC12A1
Gene Name:   solute carrier family 12 (sodium/potassium/chloride transporters), member 1
Aliases:   BSC1, MGC48843, NKCC2
RefSeq:   NC_000015.9 NG_021301.1 NT_010194.17
Ensembl:   ENSG00000074803
Entrez:   6557
UniGene:   Hs.123116
Chromosome Mapping:   15q15-q21.1

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