PrimePCR™ ddPCR™ Expression EvaGreen® Assay: ADAMTS4, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0057195; exonic

List Price:    $138.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5013760
Chromosome Location:   1:161168607-161168696question
Amplicon Length:   60

Gene Information

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules including a propeptide region a metalloproteinase domain a disintegrin-like domain and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan a major proteoglycan of cartilage and brevican a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system potentially in the progression of glioma. [provided by RefSeq Jul 2008]

Gene Symbol:   ADAMTS4
Gene Name:   ADAM metallopeptidase with thrombospondin type 1 motif, 4
Aliases:   ADAMTS-2, ADAMTS-4, ADMP-1, KIAA0688
RefSeq:   NC_000001.10 NG_013352.1 NT_004487.19
Ensembl:   ENSG00000158859
Entrez:   9507
UniGene:   Hs.211604
Chromosome Mapping:   1q21-q23

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