PrimePCR™ ddPCR™ Expression EvaGreen® Assay: TPSG1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0057114; exonic

List Price:    $138.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5013691
Chromosome Location:   16:1271729-1271878question
Amplicon Length:   120

Gene Information

Tryptases comprise a family of trypsin-like serine proteases the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. There is uncertainty regarding the number of genes in this cluster. Currently four functional genes - alpha I beta I beta II and gamma I - have been identified. And beta I has an allelic variant named alpha II beta II has an allelic variant beta III also gamma I has an allelic variant gamma II. Beta tryptases appear to be the main isoenzymes expressed in mast cells; whereas in basophils alpha-tryptases predominant. This gene differs from other members of the tryptase gene family in that it has C-terminal hydrophobic domain which may serve as a membrane anchor. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. [provided by RefSeq Jul 2008]

Gene Symbol:   TPSG1
Gene Name:   tryptase gamma 1
Aliases:   PRSS31, TMT, trpA
RefSeq:   NC_000016.9 NG_005083.1 NG_012647.1 NT_010393.16
Ensembl:   ENSG00000116176
Entrez:   25823
UniGene:   Hs.592076
Chromosome Mapping:   16p13.3

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