PrimePCR™ ddPCR™ Expression EvaGreen® Assay: STAT6, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0056844; exonic

List Price:    $138.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5013456
Chromosome Location:   12:57489602-57489751question
Amplicon Length:   120

Gene Information

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors STAT family members are phosphorylated by the receptor associated kinases and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L) which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells expression of cell surface markers and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq May 2010]

Gene Symbol:   STAT6
Gene Name:   signal transducer and activator of transcription 6, interleukin-4 induced
Aliases:   D12S1644, IL-4-STAT, STAT6B, STAT6C
RefSeq:   NC_000012.11 NT_029419.12 NG_021272.1
Ensembl:   ENSG00000166888
Entrez:   6778
UniGene:   Hs.524518
Chromosome Mapping:   12q13

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