PrimePCR™ ddPCR™ Expression EvaGreen® Assay: HP, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0048927; exonic

List Price:    $138.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5013078
Chromosome Location:   16:72088549-72090434question
Amplicon Length:   67

Gene Information

This gene encodes a preproprotein which is processed to yield both alpha and beta chains which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin which allows degradative enzymes to gain access to the hemoglobin while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy the incidence of coronary artery disease in type 1 diabetes Crohn's disease inflammatory disease behavior primary sclerosing cholangitis susceptibility to idiopathic Parkinson's disease and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   HP
Gene Name:   haptoglobin
Aliases:   BP, HP2ALPHA2, HPA1S, MGC111141
RefSeq:   NC_000016.9 NT_010498.15 NG_012651.1
Ensembl:   ENSG00000257017
Entrez:   3240
UniGene:   Hs.513711
Chromosome Mapping:   16q22.1

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