PrimePCR™ ddPCR™ Expression EvaGreen® Assay: MME, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0048099; exonic

List Price:    $138.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5012366
Chromosome Location:   3:154801987-154802096question
Amplicon Length:   80

Gene Information

This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype which represent 85% of cases of ALL. This protein is not restricted to leukemic cells however and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon enkephalins substance P neurotensin oxytocin and bradykinin. This gene which encodes a 100-kD type II transmembrane glycoprotein exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing. [provided by RefSeq Jul 2008]

Gene Symbol:   MME
Gene Name:   membrane metallo-endopeptidase
Aliases:   CALLA, CD10, DKFZp686O16152, MGC126681, MGC126707, NEP, SFE
RefSeq:   NC_000003.11 NT_005612.16
Ensembl:   ENSG00000196549
Entrez:   4311
UniGene:   Hs.307734
Chromosome Mapping:   3q25.1-q25.2

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