PrimePCR™ ddPCR™ Expression EvaGreen® Assay: USP18, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0047706; exonic

List Price:    $138.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5012013
Chromosome Location:   22:18659595-18659716question
Amplicon Length:   92

Gene Information

The protein encoded by this gene belongs to the ubiquitin-specific proteases (UBP) family of enzymes that cleave ubiquitin from ubiquitinated protein substrates. It is highly expressed in liver and thymus and is localized to the nucleus. This protein efficiently cleaves only ISG15 (a ubiquitin-like protein) fusions and deletion of this gene in mice results in a massive increase of ISG15 conjugates in tissues indicating that this protein is a major ISG15-specific protease. Mice lacking this gene are also hypersensitive to interferon suggesting a function of this protein in downregulating interferon responses independent of its isopeptidase activity towards ISG15. [provided by RefSeq Sep 2011]

Gene Symbol:   USP18
Gene Name:   ubiquitin specific peptidase 18
Aliases:   ISG43, UBP43
RefSeq:   NC_000022.10 NT_011519.10
Ensembl:   ENSG00000184979
Entrez:   11274
UniGene:   Hs.38260
Chromosome Mapping:   22q11.21

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