PrimePCR™ ddPCR™ Expression EvaGreen® Assay: SPTLC3, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0046891; exonic

List Price:    $138.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5011276
Chromosome Location:   20:13029658-13052905question
Amplicon Length:   93

Gene Information

The SPTLC3 gene encodes an isoform of the third subunit of serine palmitoyltransferase (SPT; EC which catalyzes the rate-limiting step of the de novo synthesis of sphingolipids (Hornemann et al. 2006 [PubMed 17023427]). SPT contains 2 main subunits: the common SPTLC1 subunit (MIM 605712) and either SPTLC2 (MIM 605713) or its isoform SPTLC2L (SPTLC3) depending on the tissue in which biosynthesis occurs (Hornemann et al. 2006 [PubMed 17023427]). There are also 2 highly related isoforms of a third subunit SSSPTA (MIM 613540) and SSSPTB (MIM 610412) that confer acyl-CoA preference of the SPT enzyme and are essential for maximal enzyme activity (Han et al. 2009 [PubMed 19416851]).[supplied by OMIM Nov 2010]

Gene Symbol:   SPTLC3
Gene Name:   serine palmitoyltransferase, long chain base subunit 3
Aliases:   C20orf38, FLJ11112, FLJ90790, LCB2B, LCB3, SPT3, SPTLC2L, dJ718P11, dJ718P11.1
RefSeq:   NC_000020.10 NT_011387.8
Ensembl:   ENSG00000172296
Entrez:   55304
UniGene:   Hs.425023
Chromosome Mapping:   20p12.1

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