PrimePCR™ ddPCR™ Expression EvaGreen® Assay: COMT, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0042669; exonic

List Price:    $138.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5007522
Chromosome Location:   22:19950146-19950236question
Amplicon Length:   61

Gene Information

Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines including the neurotransmitters dopamine epinephrine and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances COMT is important in the metabolism of catechol drugs used in the treatment of hypertension asthma and Parkinson disease. COMT is found in two forms in tissues a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters. [provided by RefSeq Sep 2008]

Gene Symbol:   COMT
Gene Name:   catechol-O-methyltransferase
Aliases:   Not Available
RefSeq:   NC_000022.10 NG_011526.1 NG_011835.1 NG_023326.1 NT_011519.10
Ensembl:   ENSG00000093010
Entrez:   1312
UniGene:   Hs.370408
Chromosome Mapping:   22q11.21-q11.23,22q11.21

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