PrimePCR™ ddPCR™ Expression EvaGreen® Assay: SLC46A1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR Evagreen assay for gene expression analysis. EvaGreen assays consist of unlabeled PCR primer.

Info:   EG; Same primer pair as used in qPCR assay qHsaCED0037938; exonic

List Price:    $138.00
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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5006330
Chromosome Location:   17:26732190-26732298question
Amplicon Length:   79

Gene Information

This gene encodes a transmembrane proton-coupled folate transporter protein that facilitates the movement of folate and antifolate substrates across cell membranes optimally in acidic pH environments. This protein is also expressed in the brain and choroid plexus where it transports folates into the central nervous system. This protein further functions as a heme transporter in duodenal enterocytes and potentially in other tissues like liver and kidney. Its localization to the apical membrane or cytoplasm of intestinal cells is modulated by dietary iron levels. Mutations in this gene are associated with autosomal recessive hereditary folate malabsorption (HFM) disease. HFM is characterized by folate deficiency due to reduced intestinal folate absorption and subsequent anemia hypoimmunoglobulinemia and recurrent infections. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq Jun 2011]

Gene Symbol:   SLC46A1
Gene Name:   solute carrier family 46 (folate transporter), member 1
Aliases:   FLJ39875, HCP1, MGC9564, PCFT
RefSeq:   NC_000017.10 NG_013306.1 NT_010799.15
Ensembl:   ENSG00000076351
Entrez:   113235
UniGene:   Hs.731770
Chromosome Mapping:   17q11.2

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