PrimePCR™ ddPCR™ Expression Probe Assay: FKBP1A, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0041373; Intron-spanning

 
Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5193392
Chromosome Location:   20:1352778-1356176question
Amplicon Length:   119

Gene Information

The protein encoded by this gene is a member of the immunophilin protein family which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants encoding the same protein have been identified. The human genome contains five pseudogenes related to this gene at least one of which is transcribed. [provided by RefSeq Sep 2008]

Gene Symbol:   FKBP1A
Gene Name:   FK506 binding protein 1A, 12kDa
Aliases:   FKBP-12, FKBP1, FKBP12, PKC12, PKCI2, PPIASE
RefSeq:   NC_000020.10 NT_011387.8
Ensembl:   ENSG00000088832
Entrez:   2280
UniGene:   Hs.471933
Chromosome Mapping:   20p13

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