This is the amplicon context sequence in accordance with the minimum information for the publication of real-time quantitative PCR experiements (MIQE) guidelines. For more details, please refer to the following publication, "Primer Sequence Disclosure: A Clarification of the MIQE Guidelines."
ddPCR™ probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.
Info: HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0049598; exonic
The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein either alone or when in the SWI/SNF complex can bind to 4-way junction DNA which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins this protein has no yeast counterpart. [provided by RefSeq Jul 2008]