PrimePCR™ ddPCR™ Expression Probe Assay: PRG2, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0040971; exonic

Fluorophore:   FAM
List Price:    $213.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5191257
Chromosome Location:   11:57156531-57156685question
Amplicon Length:   125

Gene Information

The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA) angiotensinogen (AGT) and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin and in immune hypersensitivity reactions. It is directly implicated in epithelial cell damage exfoliation and bronchospasm in allergic diseases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Aug 2011]

Gene Symbol:   PRG2
Gene Name:   proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
Aliases:   BMPG, MBP, MBP1, MGC14537
RefSeq:   NC_000011.9 NT_167190.1
Ensembl:   ENSG00000186652
Entrez:   5553
UniGene:   Hs.512633
Chromosome Mapping:   11q12

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