PrimePCR™ ddPCR™ Expression Probe Assay: CASP7, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0039459; Intron-spanning

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5058672
Chromosome Location:   10:115481504-115485208question
Amplicon Length:   93

Gene Information

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits large and small that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase 3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants encoding three distinct isoforms. [provided by RefSeq Jul 2008]

Gene Symbol:   CASP7
Gene Name:   caspase 7, apoptosis-related cysteine peptidase
Aliases:   CMH-1, ICE-LAP3, MCH3
RefSeq:   NC_000010.10 NT_030059.13
Ensembl:   ENSG00000165806
Entrez:   840
UniGene:   Hs.9216
Chromosome Mapping:   10q25

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