PrimePCR™ ddPCR™ Expression Probe Assay: SPTLC1, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0039076; Intron-spanning

 
Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5058425
Chromosome Location:   9:94842315-94843193question
Amplicon Length:   68

Gene Information

Serine palmitoyltransferase which consists of two different subunits is the key enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor. The product of this gene is the long chain base subunit 1 of serine palmitoyltransferase. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. [provided by RefSeq Jul 2008]

Gene Symbol:   SPTLC1
Gene Name:   serine palmitoyltransferase, long chain base subunit 1
Aliases:   HSAN, HSAN1, HSN1, LBC1, LCB1, MGC14645, SPT1, SPTI
RefSeq:   NC_000009.11 NG_007950.1 NT_008470.19
Ensembl:   ENSG00000090054
Entrez:   10558
UniGene:   Hs.90458
Chromosome Mapping:   9q22.2

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