PrimePCR™ ddPCR™ Expression Probe Assay: MATK, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0030891; Intron-spanning

 
Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5055027
Chromosome Location:   19:3779726-3783142question
Amplicon Length:   124

Gene Information

The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains a catalytic domain a unique N terminus lack of myristylation signals lack of a negative regulatory phosphorylation site and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   MATK
Gene Name:   megakaryocyte-associated tyrosine kinase
Aliases:   CHK, CTK, DKFZp434N1212, HHYLTK, HYL, HYLTK, Lsk, MGC1708, MGC2101
RefSeq:   NC_000019.9 NT_011255.14
Ensembl:   ENSG00000007264
Entrez:   4145
UniGene:   Hs.631845
Chromosome Mapping:   19p13.3

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