PrimePCR™ ddPCR™ Expression Probe Assay: KCNQ3, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0030543; Intron-spanning

 
Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5054373
Chromosome Location:   8:133146552-133150223question
Amplicon Length:   146

Gene Information

The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and one of two related proteins encoded by the KCNQ2 and KCNQ5 genes both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 2 (BFNC2) also known as epilepsy benign neonatal type 2 (EBN2). Two variants encoding distinct isoforms have been found. [provided by RefSeq Mar 2011]

Gene Symbol:   KCNQ3
Gene Name:   potassium voltage-gated channel, KQT-like subfamily, member 3
Aliases:   BFNC2, DKFZp686C0248, EBN2, FLJ37386, FLJ38392, KV7.3
RefSeq:   NC_000008.10 NG_008854.1 NT_008046.16
Ensembl:   ENSG00000184156
Entrez:   3786
UniGene:   Hs.374023
Chromosome Mapping:   8q24

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