PrimePCR™ ddPCR™ Expression Probe Assay: SLC6A4, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0030472; Intron-spanning

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5054238
Chromosome Location:   17:28525456-28530244question
Amplicon Length:   118

Gene Information

This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants such as amphetamines and cocaine and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome aggressive behavior in Alzheimer disease patients and depression-susceptibility in people experiencing emotional trauma. [provided by RefSeq Jul 2008]

Gene Symbol:   SLC6A4
Gene Name:   solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
Aliases:   5-HTT, 5-HTTLPR, 5HTT, HTT, OCD1, SERT, hSERT
RefSeq:   NC_000017.10 NG_011747.1 NT_010799.15
Ensembl:   ENSG00000108576
Entrez:   6532
UniGene:   Hs.134662
Chromosome Mapping:   17q11.2

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