PrimePCR™ ddPCR™ Expression Probe Assay: VPS4B, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0030229; Intron-spanning

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5053778
Chromosome Location:   18:61060701-61064323question
Amplicon Length:   109

Gene Information

The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities) and is the homolog of the yeast Vps4 protein. In humans two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments and are involved in intracellular protein trafficking similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 18; the gene for the other resides on chromosome 16. [provided by RefSeq Jul 2008]

Gene Symbol:   VPS4B
Gene Name:   vacuolar protein sorting 4 homolog B (S. cerevisiae)
Aliases:   SKD1, SKD1B, VPS4-2
RefSeq:   NC_000018.9 NT_025028.14
Ensembl:   ENSG00000119541
Entrez:   9525
UniGene:   Hs.126550
Chromosome Mapping:   18q21.33

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