PrimePCR™ ddPCR™ Expression Probe Assay: NDUFA1, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0030172; Intron-spanning

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5053667
Chromosome Location:   X:119007282-119010574question
Amplicon Length:   143

Gene Information

The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane. However the NDUFA1 peptide is one of about 31 components of the "hydrophobic protein" (HP) fraction of complex I which is involved in proton translocation. Thus the NDUFA1 peptide may also participate in that function. [provided by RefSeq Jul 2008]

Gene Symbol:   NDUFA1
Gene Name:   NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
Aliases:   CI-MWFE, MWFE, ZNF183
RefSeq:   NC_000023.10 NG_009381.1 NG_021227.1 NT_011786.16
Ensembl:   ENSG00000125356
Entrez:   4694
UniGene:   Hs.534168
Chromosome Mapping:   Xq24

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