PrimePCR™ ddPCR™ Expression Probe Assay: CPB2, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0030103; Intron-spanning

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5053534
Chromosome Location:   13:46632444-46638844question
Amplicon Length:   105

Gene Information

Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo- serine and cysteine carboxypeptidases. According to their substrate specificity these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. [provided by RefSeq Apr 2012]

Gene Symbol:   CPB2
Gene Name:   carboxypeptidase B2 (plasma)
Aliases:   CPU, PCPB, TAFI
RefSeq:   NC_000013.10 NT_024524.14
Ensembl:   ENSG00000080618
Entrez:   1361
UniGene:   Hs.512937
Chromosome Mapping:   13q14.11

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