PrimePCR™ ddPCR™ Expression Probe Assay: RASA3, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0030094; Intron-spanning

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5053516
Chromosome Location:   13:114786891-114789811question
Amplicon Length:   121

Gene Information

The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS thereby allowing control of cellular proliferation and differentiation. This family member is an inositol 1345-tetrakisphosphate-binding protein like the closely related RAS p21 protein activator 2. The two family members have distinct pleckstrin-homology domains with this particular member having a domain consistent with its localization to the plasma membrane. [provided by RefSeq Jul 2008]

Gene Symbol:   RASA3
Gene Name:   RAS p21 protein activator 3
Aliases:   GAP1IP4BP, GAPIII, MGC46517, MGC47588
RefSeq:   NC_000013.10 NT_024498.12
Ensembl:   ENSG00000185989
Entrez:   22821
UniGene:   Hs.593075
Chromosome Mapping:   13q34

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