PrimePCR™ ddPCR™ Expression Probe Assay: NLRP7, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0030026; Intron-spanning

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5053389
Chromosome Location:   19:55445950-55447671question
Amplicon Length:   91

Gene Information

This gene encodes a member of the NACHT leucine rich repeat and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain followed by a NACHT domain a NACHT-associated domain (NAD) and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq Jul 2008]

Gene Symbol:   NLRP7
Gene Name:   NLR family, pyrin domain containing 7
Aliases:   CLR19.4, FLJ94610, HYDM, MGC126470, MGC126471, NALP7, NOD12, PAN7, PYPAF3
RefSeq:   NC_000019.9 NG_008056.1 NT_011109.16
Ensembl:   ENSG00000167634
Entrez:   199713
UniGene:   Hs.351118
Chromosome Mapping:   19q13.42

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