PrimePCR™ ddPCR™ Expression Probe Assay: PSMB1, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0029749; Intron-spanning

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5052879
Chromosome Location:   6:170846367-170852762question
Amplicon Length:   106

Gene Information

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome the immunoproteasome is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family also known as the T1B family that is a 20S core beta subunit. This gene is tightly linked to the TBP (TATA-binding protein) gene in human and in mouse and is transcribed in the opposite orientation in both species. [provided by RefSeq Jul 2008]

Gene Symbol:   PSMB1
Gene Name:   proteasome (prosome, macropain) subunit, beta type, 1
Aliases:   FLJ25321, HC5, KIAA1838, PMSB1, PSC5
RefSeq:   NC_000006.11 NG_008165.1 NT_025741.15
Ensembl:   ENSG00000008018
Entrez:   5689
UniGene:   Hs.352768
Chromosome Mapping:   6q27

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