PrimePCR™ ddPCR™ Expression Probe Assay: PIK3CG, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0029621; Intron-spanning

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5052654
Chromosome Location:   7:106520082-106523515question
Amplicon Length:   128

Gene Information

This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals including those elicited by E-cadherin-mediated cell-cell adhesion which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. [provided by RefSeq Jul 2008]

Gene Symbol:   PIK3CG
Gene Name:   phosphoinositide-3-kinase, catalytic, gamma polypeptide
Aliases:   PI3CG, PI3K, PI3Kgamma, PIK3
RefSeq:   NC_000007.13 NT_007933.15
Ensembl:   ENSG00000105851
Entrez:   5294
UniGene:   Hs.32942
Chromosome Mapping:   7q22.3

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