PrimePCR™ ddPCR™ Expression Probe Assay: TNFRSF10C, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0029459; Intron-spanning

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5052380
Chromosome Location:   8:22973021-22974228question
Amplicon Length:   154

Gene Information

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq Jul 2008]

Gene Symbol:   TNFRSF10C
Gene Name:   tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
Aliases:   CD263, DCR1, DCR1-TNFR, LIT, MGC149501, MGC149502, TRAIL-R3, TRAILR3, TRID
RefSeq:   NC_000008.10 NT_167187.1
Ensembl:   ENSG00000173535
Entrez:   8794
UniGene:   Hs.655801
Chromosome Mapping:   8p22-p21

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