PrimePCR™ ddPCR™ Expression Probe Assay: PIM1, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0029454; Intron-spanning

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5052371
Chromosome Location:   6:37140867-37141837question
Amplicon Length:   180

Gene Information

The protein encoded by this gene belongs to the Ser/Thr protein kinase family and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells contributing to both cell proliferation and survival and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805 1825810).[provided by RefSeq Aug 2011]

Gene Symbol:   PIM1
Gene Name:   pim-1 oncogene
Aliases:   PIM
RefSeq:   NC_000006.11 NT_007592.15
Ensembl:   ENSG00000137193
Entrez:   5292
UniGene:   Hs.81170
Chromosome Mapping:   6p21.2

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