PrimePCR™ ddPCR™ Expression Probe Assay: SIRT6, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0029310; Intron-spanning

 
Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5052126
Chromosome Location:   19:4177076-4179265question
Amplicon Length:   195

Gene Information

This gene encodes a member of the sirtuin family of proteins homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. Alternative splicing results in multiple transcript variants.[provided by RefSeq Jul 2010]

Gene Symbol:   SIRT6
Gene Name:   sirtuin 6
Aliases:   SIR2L6
RefSeq:   NC_000019.9 NT_011255.14
Ensembl:   ENSG00000077463
Entrez:   51548
UniGene:   Hs.423756
Chromosome Mapping:   19p13.3

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