PrimePCR™ ddPCR™ Expression Probe Assay: PDCD1, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0029261; Intron-spanning

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5052050
Chromosome Location:   2:242795025-242800950question
Amplicon Length:   114

Gene Information

This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq Jul 2008]

Gene Symbol:   PDCD1
Gene Name:   programmed cell death 1
Aliases:   CD279, PD-1, PD1, SLEB2, hPD-1, hPD-l
RefSeq:   NC_000002.11 NG_012110.1 NT_005416.13
Ensembl:   ENSG00000188389
Entrez:   5133
UniGene:   Hs.158297
Chromosome Mapping:   2q37.3

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