PrimePCR™ ddPCR™ Expression Probe Assay: AMACR, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0029215; Intron-spanning

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5051973
Chromosome Location:   5:34005907-34007980question
Amplicon Length:   171

Gene Information

This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy pigmentary retinopathy and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq Mar 2011]

Gene Symbol:   AMACR
Gene Name:   alpha-methylacyl-CoA racemase
Aliases:   CBAS4, RACE, RM
RefSeq:   NC_000005.9 NG_011691.1 NT_006576.16 NG_016211.1
Ensembl:   ENSG00000242110
Entrez:   23600
UniGene:   Hs.508343
Chromosome Mapping:   5p13

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