PrimePCR™ ddPCR™ Expression Probe Assay: TXNRD1, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0028905; Intron-spanning

 
Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5051477
Chromosome Location:   12:104719133-104720164question
Amplicon Length:   85

Gene Information

This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure the sec insertion sequence (SECIS) that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms. [provided by RefSeq Jul 2008]

Gene Symbol:   TXNRD1
Gene Name:   thioredoxin reductase 1
Aliases:   GRIM-12, MGC9145, TR, TR1, TRXR1, TXNR
RefSeq:   NC_000012.11 NT_029419.12
Ensembl:   ENSG00000198431
Entrez:   7296
UniGene:   Hs.715771
Chromosome Mapping:   12q23-q24.1

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