PrimePCR™ ddPCR™ Expression Probe Assay: FCN3, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0028896; Intron-spanning

 
Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5051458
Chromosome Location:   1:27697384-27699712question
Amplicon Length:   136

Gene Information

Ficolins are a group of proteins which consist of a collagen-like domain and a fibrinogen-like domain. In human serum there are two types of ficolins both of which have lectin activity. The protein encoded by this gene is a thermolabile beta-2-macroglycoprotein found in all human serum and is a member of the ficolin/opsonin p35 lectin family. The protein which was initially identified based on its reactivity with sera from patients with systemic lupus erythematosus has been shown to have a calcium-independent lectin activity. The protein can activate the complement pathway in association with MASPs and sMAP thereby aiding in host defense through the activation of the lectin pathway. Alternative splicing occurs at this locus and two variants each encoding a distinct isoform have been identified. [provided by RefSeq Jul 2008]

Gene Symbol:   FCN3
Gene Name:   ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen)
Aliases:   FCNH, HAKA1, MGC22543
RefSeq:   NC_000001.10 NG_016279.1 NT_004610.19
Ensembl:   ENSG00000142748
Entrez:   8547
UniGene:   Hs.333383
Chromosome Mapping:   1p36.11

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