PrimePCR™ ddPCR™ Expression Probe Assay: ATP1A2, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0028855; Intron-spanning

 
Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5051391
Chromosome Location:   1:160094091-160094973question
Amplicon Length:   148

Gene Information

The protein encoded by this gene belongs to the family of P-type cation transport ATPases and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation for sodium-coupled transport of a variety of organic and inorganic molecules and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 2 subunit. Mutations in this gene result in familial basilar or hemiplegic migraines and in a rare syndrome known as alternating hemiplegia of childhood. [provided by RefSeq Oct 2008]

Gene Symbol:   ATP1A2
Gene Name:   ATPase, Na+/K+ transporting, alpha 2 polypeptide
Aliases:   FHM2, MGC59864, MHP2
RefSeq:   NC_000001.10 NG_008014.1 NT_004487.19
Ensembl:   ENSG00000018625
Entrez:   477
UniGene:   Hs.34114
Chromosome Mapping:   1q21-q23

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