PrimePCR™ ddPCR™ Expression Probe Assay: PTPRF, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0028797; Intron-spanning

 
Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5051295
Chromosome Location:   1:44057548-44058209question
Amplicon Length:   124

Gene Information

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth differentiation mitotic cycle and oncogenic transformation. This PTP possesses an extracellular region a single transmembrane region and two tandem intracytoplasmic catalytic domains and thus represents a receptor-type PTP. The extracellular region contains three Ig-like domains and nine non-Ig like domains similar to that of neural-cell adhesion molecule. This PTP was shown to function in the regulation of epithelial cell-cell contacts at adherents junctions as well as in the control of beta-catenin signaling. An increased expression level of this protein was found in the insulin-responsive tissue of obese insulin-resistant individuals and may contribute to the pathogenesis of insulin resistance. Two alternatively spliced transcript variants of this gene which encode distinct proteins have been reported. [provided by RefSeq Jul 2008]

Gene Symbol:   PTPRF
Gene Name:   protein tyrosine phosphatase, receptor type, F
Aliases:   FLJ43335, FLJ45062, FLJ45567, LAR
RefSeq:   NC_000001.10 NT_032977.9
Ensembl:   ENSG00000142949
Entrez:   5792
UniGene:   Hs.272062
Chromosome Mapping:   1p34

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