PrimePCR™ ddPCR™ Expression Probe Assay: ITGA2B, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0028772; Intron-spanning

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5051262
Chromosome Location:   17:42453686-42454456question
Amplicon Length:   121

Gene Information

ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion integrins are known to participate in cell-surface mediated signalling. [provided by RefSeq Jul 2008]

Gene Symbol:   ITGA2B
Gene Name:   integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
Aliases:   CD41, CD41B, GP2B, GPIIb, GTA, HPA3
RefSeq:   NC_000017.10 NG_008331.1 NT_010783.15
Ensembl:   ENSG00000005961
Entrez:   3674
UniGene:   Hs.411312
Chromosome Mapping:   17q21.32

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